Print
clock clock iconcutlery cutlery iconflag flag iconfolder folder iconinstagram instagram iconpinterest pinterest iconfacebook facebook iconprint print iconsquares squares iconheart heart iconheart solid heart solid icon
Creamy Sour Cream Chicken Casserole Recipe

Creamy Sour Cream Chicken Casserole Recipe


5 Stars 4 Stars 3 Stars 2 Stars 1 Star

4.6 from 26 reviews

  • Total Time: 1 hour 15 minutes
  • Yield: 5 1x

Description

Mexican-inspired Cheesy Sour Cream Chicken Casserole blends zesty flavors with creamy comfort. Hearty ingredients create a satisfying meal you’ll crave for family dinners and potluck gatherings.


Ingredients

Scale
  • 4 boneless, skinless chicken breasts (about 1.4 kg / 3 pounds)
  • ¾ cup (180 ml) finely shredded Parmesan cheese
  • 4 slices mozzarella cheese
  • 1 cup (240 ml) rich sour cream
  • 1 tbsp cornstarch
  • 1 tsp garlic powder
  • 1 tsp dried oregano
  • 1 pinch of salt
  • 1 pinch of black pepper
  • Cooking oil (for greasing the dish)

Instructions

  1. Preparation: Preheat oven to 375°F (190°C) and thoroughly grease a 9×13-inch baking dish with cooking spray, ensuring complete surface coverage.
  2. Chicken Layering: Arrange chicken breasts in a single layer within the prepared dish, seasoning generously with kosher salt and black pepper to maximize flavor depth.
  3. Sauce Creation: Whisk sour cream, Parmesan cheese, oregano, garlic powder, cornstarch, salt, and pepper in a medium bowl until achieving a silky, uniform consistency that will coat the chicken perfectly.
  4. Cheese Integration: Position a mozzarella slice atop each chicken breast, creating a rich, melty foundation for the upcoming sauce layer.
  5. Sauce Application: Distribute the sour cream mixture evenly across the mozzarella-topped chicken, ensuring complete and uniform coverage that promises exceptional taste in every bite.
  6. Cheese Topping: Liberally sprinkle remaining Parmesan cheese over the surface, developing a golden, crispy cheese crust that will caramelize during baking.
  7. Baking Process: Slide the baking dish into the preheated oven and roast for 50-60 minutes, monitoring until chicken reaches 165°F (74°C) internal temperature and cheese transforms into a bubbling, bronzed masterpiece.
  8. Resting Phase: Extract the casserole from the oven and allow 5-7 minutes of resting time, permitting sauce to thicken and flavors to harmonize deliciously.
  9. Final Touch: Garnish with freshly chopped parsley or chives, adding a vibrant, herbaceous accent that elevates the entire dish’s visual and flavor profile.

Notes

  • Chicken Temperature Check: Always use a meat thermometer to confirm chicken reaches 165°F (74°C) for safe consumption, preventing potential foodborne illnesses.
  • Cheese Melting Tip: Use freshly grated cheese instead of pre-shredded varieties for smoother melting and richer flavor development.
  • Moisture Preservation: Cover the casserole with aluminum foil during initial baking to prevent chicken from drying out, removing foil in the last 15 minutes for cheese browning.
  • Ingredient Substitution: Can replace sour cream with Greek yogurt for a lighter version without compromising the creamy texture and tangy flavor profile.
  • Prep Time: 15 minutes
  • Cook Time: 1 hour
  • Category: Dinner, Lunch
  • Method: Baking
  • Cuisine: American

Nutrition

  • Serving Size: 5
  • Calories: 478
  • Sugar: 2 g
  • Sodium: 503 mg
  • Fat: 22 g
  • Saturated Fat: 12 g
  • Unsaturated Fat: 8 g
  • Trans Fat: 0 g
  • Carbohydrates: 27 g
  • Fiber: 0 g
  • Protein: 44 g
  • Cholesterol: 138 mg